Genetic Analysis and Species Specific Amplification of the Artemisinin Resistance-Associated Kelch Propeller Domain in P. falciparum and P. vivax.
Plasmodium falciparum resistance to artemisinin has emerged in the Greater Mekong Subregion and now poses a threat shure ua874 to malaria control and prevention.Recent work has identified mutations in the kelch propeller domain of the P.falciparum K13 gene to be associated artemisinin resistance as defined by delayed parasite clearance and ex vivo